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Objective inflammation assessment: Depending on the clinical situation, assessment may include blood tests, stool markers such as faecal calprotectin, imaging, colonoscopy, gastroscopy or other investigations to understand whether symptoms are linked to active inflammation or another gut condition

Furthermore, the credibility of the findings should be regarding the possibility that the final endpoint of these concepts (cytoprotection organoprotection [41,42,43,44,45,46,47,48,49], reestablished body homeostasis [59,60,61]), response as such as claimed by both Robert and Selye [41,59], could ever be realized by the pharmacologic agent

Optic nerve damage: Particularly in individuals with Leber's disease, a hereditary condition that causes retinal degeneration and blindness in children