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Management and prevention of breast cancer after radiation to the chest for childhood, adolescent, and young adulthood malignancy

In preclinical rat studies, our biochemical plumber has been shown to lay down new pipes by inducing angiogenesisthe formation of new blood vessels that carry vital nutrients and remove waste (Sikiric et al

doi: 10.1038/mp.2017.205 68 BeurelELowellJA

Initially, we focused on peptides with a spacing between histidine residues of a single glycine G(HG) x (x=1-4), as this could in principle allow tetra-dentate binding with two histidine imidazole groups and two backbone nitrogen atoms (Fig