(PubMed) Wilhelm SM, Rjater RG, Kale-Pradhan PB
28 However, oral therapy does not improve serum methylmalonic acid levels as well as intramuscular therapy, although the clinical relevance is unclear
Current areas of scientific investigation include telomere-associated pathway analysis, cellular aging and replication signaling studies, transcriptional and epigenetic regulation research, circadian and pineal-associated signaling investigations, genomic stability pathway research, and intracellular signaling network evaluation
In case of neurologic symptoms or abnormalities, it is suggested to administer hydroxocobalamin, 1000 mg once or twice weekly for a period of up to 2 years, and the package insert for hydroxocobalamin has included these particular instructions for several decades