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Updated phase I trial of anti-LAG-3 or anti-CD137 alone and in combination with anti-PD-1 in patients with recurrent GBM

routine B12 level monitoring is generally unnecessary once replacement is established, as levels do not reliably correlate with tissue stores Important safety considerations: Older adults may have impaired renal function, though this rarely affects B12 therapy given its wide safety margin

WHY METHYLCOBALAMIN MATTERS: Unlike other forms of B12, methylcobalamin is already in its active formmeaning your pets body can absorb and use it more efficiently without needing to convert it first

PMC 2895704