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In the control rats with a large lesion area and at the border of bone tissue and muscle, there was significant edema and no reaction of periosteum for mesenchymal stem cells (i.e., on post-operative day 2) (Figure 14)

Importantly, these body weight changes were not attributable to differences in food intake across the groups, as all treatments showed similar food consumption patterns in both lean and obese mice

The stable nature of the substance makes sure that batch quality stays the same during large-scale production runs