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When it was first identified as part of a bigger protein in the digestive system, researchers were curious about how it behaved in different tissues, including muscle, tendons, ligaments, nerves, and gut tissue

Since MMPs are the primary mediators of BBB disruption and hence HT, its inhibition at the early stages of stroke is of great relevance

Juxtavascular microglia, which are brain tissue-resident macrophages, enhance brain repair by removing toxic debris, reducing neuroinflammation and releasing trophic factors (215)

Research indicates that oral delivery of DSIP is not as effective due to its structure and absorption properties