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These drugs exemplify how targeting specific virulence factors can disarm pathogens while boosting the efficacy of existing antibiotics

Feeling the effects: Youll usually start to feel the energizing effects of a B12 shot within a short time, often within minutes or an hour

Without treatment, this leads to megaloblastic anaemia and potentially serious neurological complications

Furthermore, addition of exogenous GSSG also increased PhoA activity in the WT, contrary to what we observed with roGFP2, suggesting that the role of periplasmic glutathione in oxidative folding differs, depending on the protein in question (Fig