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Site rotation: Systematically rotate injection sites between abdomen (at least 2 inches from navel), outer thighs, and upper arms to reduce local irritation and prevent tissue hardening [8]

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The selectivity arises because senescent cells are uniquely dependent on FOXO4-mediated p53 sequestration for survival, while non-senescent cells employ multiple redundant anti-apoptotic mechanisms

Risk Summary The pregnancy risk summary provides a concise summary of what is known about medication use during pregnancy