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Tirzepatide also has a relatively long half-life, estimated at around five days

In addition to its catalytic activity, aldolase has been reported to have several moonlighting functions such as WASP and actin binding 34,35,36 , regulation of endocytosis via SNX9 37 and modulation of AMPK signalling 38,39

Notably, GHK-Cu was originally identified as a liver cell growth factor, recognized for its role in stimulating liver tissue regeneration and its significance in age-related tissue repair

Given that GpoA plays a protective role against oxidative stress, we investigated whether deletion of the gpoA gene would impact on levofloxacin persistence