Disclosure of interest: All authors: Nothing to disclose E-Posters - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P2354 - ESOC25-772 UTILITY OF PRO-ADRENOMEDULLIN DETERMINATION IN THE STROKE CODE: PRESTO STUDY Cristina Sanabria Gago 1 , Raquel Berbegal Serralta 1 , Jaime Alonso 1 , Vanesa Escribano 2 , Beln Colino Galian 2 , Elena Salgado Barbado 2 , Mnica Sobrado Sanz 3 , Carmen Ramos 1 , Alvaro Ximnez-Carrillo 1 , Elisa de la Fuente Sanz 1 , Alicia Gonzalez-Martinez 1 , Carmen Snchez-Rodrguez 1 , Alba Somovilla 1 , Jose Vivancos 1 , Santiago Trillo Senin 1 1 Neurology Department
The presence of a disulfide bridge, combined with the addition of tyrosine at the N-terminus, significantly enhances the peptides stability, making it orally active [8]
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BBB disruption in the TL may be linked to anosmia because it contains important regions that form part of the primary olfactory cortex, including the piriform cortex, amygdala and entorhinal cortex, with direct connections to and from the olfactory bulb 33,34,35
