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Collectively, these data indicate that GSK3-mediated phosphorylation generates a phospho-degron within the CPD motif of ETV6, facilitating recognition by FBXW7 and subsequent ETV6 degradation

They wrote: Remarkably, under the optimized micelle conditions, A42 assembles into oligomers that insert into lipid bilayers as well-defined pores and adopt a specific structure with characteristics of a -barrel arrangement (Zhaliazka et al., 2023)

Understanding these interactions is crucial to avoid complications such as hypoglycemia (low blood sugar), bleeding, or reduced therapeutic benefits

The generation of mutants for selected genes based on transcriptomic data, using advanced techniques such as CRISPR/Cas9, will further open new horizons for developing resistance to viruses or other multifactorial stresses