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[2] After the promising results from the 12-week trial, a more extended 24-week trial was conducted with a larger group of 536 subjects

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At the border of the bone tissue, the reaction of the periosteum was visible, the formation of bone tissue was organized, the diameter of the bone was larger, and the proliferation of mesenchymal stem cells and close contact with the muscle fibers were still observed on the surface (Figure 16)