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In addition, when studying environmental cancer risk factors, it is important to consider that exposure to several environmental cancer risk factors may occur simultaneously

In addition to nicotine, vaping liquids typically contain glycerol (vegetable glycerin) and propylene glycol (PG), and chemicals used for flavouring

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Nicotinamide restriction with subsequent depletion of cellular NAD was shown to increase oxidative stress-induced DNA damage in a precancerous skin cell model, implying a protective role of NAD-dependent pathways in cancer (63)