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Dopamine, norepinephrine, serotonin, glutamate, aminobutyric acid (GABA) and opioid peptides are neurotransmitter systems influenced by nAChRs (58)

However, there are several telltale signs to watch for: In Adults: Feeling of fullness or pressure in the ear Muffled or decreased hearing Popping or crackling sounds when swallowing or yawning Balance problems or mild dizziness Tinnitus (ringing in the ears) Difficulty hearing high-pitched sounds or understanding conversations in noisy environments In Children: Pulling or tugging at the ears Inattentiveness or difficulty responding when called Turning up the volume on electronic devices Speaking louder than usual Balance issues or clumsiness Delayed speech development (in persistent cases) Unlike acute ear infections, fluid in the ear typically develops gradually and may persist for weeks or even months without treatment