Our study demonstrated that naltrexone significantly attenuated the acute increase in Glx/tNAA during ketamine infusion compared to placebo, implying a potential interaction between opioidergic and glutamatergic systems, which may be of importance in understanding ketamines neurobiological effects
Furthermore, the relatively small genetic influence on serum UA implies a greater contribution from other factors, perhaps those environmentally mediated
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Abbreviations Traumatic brain injury, TBI
