Tercukupinya kadar glutathione mampu menangkal radikal bebas dan mendetoksifikasi zat penyebab kanker (karsinogenik), sehingga efektif mencegah kerusakan sel tubuh
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Because of that, plants developed complexed ROS control system based on enzymes (like glutathione reductase-GR, glutathione S-transferase-GST, glutathione peroxidase-GPX) and scavenging non-enzymatic hydrophilic molecules like ascorbate (AsA) and glutathione (GSH) (Noctor and Foyer, 1998)
Using erastin-treated A549 cells, we measured intracellular Fe 2+ , ROS, lipid peroxide, glutathione, glutamate release into the extracellular space, and cystine uptake