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This work was supported by the National Natural Science Foundation of China (92357306, 82495190, 82271722, 82301931, 82088102), National Key R&D Program of China (2022YFC2703500), Fund of Fudan University and Caoejiang Basic Research (24FCA14), Collaborative Innovation Program of Shanghai Municipal Health Commission (2020CXJQ01), Shanghai Clinical Research Center for Gynecological Diseases (22MC1940200), Shanghai Urogenital System Diseases Research Center (2022ZZ01012)