Label every vial with name, concentration, reconstitution date, and 28-day discard date
Higher-frequency or higher-volume experimental protocols may increase the likelihood of sensitivity-related observations or tolerability concerns
In patients with T2DM who do not have atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, HF, or CKD and who need to minimize hypoglycemia and/or promote weight loss, GLP-1 RAs are generally recommended as a second or third-line option as add-on to metformin therapy
However, in MCAS, these cells become highly unstable and overly sensitive, inappropriately degranulating and flooding the body with histamine in response to benign triggers like food, temperature changes, or even emotional stress