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(2003) Differences in the involvement of prostanoids from Kupffer cells in the meditation of anaphylylatoxin C5a-, zymosan-, and lipopolysaccharide-dependent hepatic glucose output and flow reduction Lab

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These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005

It plays a central role in liver detox pathways