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S-Adenosyl methionine improves motor co-ordination with reduced oxidative stress, dopaminergic neuronal loss, and DNA methylation in the brain striatum of 6-Hydroxydopamine-induced neurodegeneration in rats

Ongoing Clinical Trials Numerous questions remain under investigation, including: Long-term biological effects Extended safety profiles Pharmacodynamic characteristics Receptor-level adaptations Combination therapy applications As a result, ongoing clinical trials continue to generate new information regarding the compounds biological activity and potential future applications

Oksanen M, Petersen AJ, Naumenko N, Puttonen K, Lehtonen S, Oliv MG, Shakirzyanova A, Leskel S, Sarajrvi T, Viitanen M, Rinne JO, Hiltunen M, Haapasalo A, Giniatullin R, Tavi P, Zhang S-C, Kanninen KM, Hmlinen RH, Koistinaho J