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The skin's tissue is divided into two layers: the top epidermis, which is made up of epithelial cells and pigmented melanocytes, and the bottom dermis, which comprises a layer of connective tissue that holds blood vessels, hair follicles, and sweat glands [9,10,11,12,13]

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This complex biological process that causes clinical symptoms, including heat, pain, redness, and swelling, is broadly triggered by infection and tissue damage [2]

Furthermore, alterations in plasma acylcarnitine concentrations are linked to the reductions in muscle mass and strength associated with Graves disease