, In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds., American Society for Clinical Investigation, Nov
Research perspective A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe" based on the lack of lethal doses in animal studies and absence of significant side effects in human trials beyond transient symptoms
Four studies found no significant difference in serum or plasma serine levels between children and adults with or without autistic disorder, PDD-NOS, Asperger's Syndrome or autism spectrum disorders (mixed sample) [60, 69, 70, 75], one study showed a trend towards a decrease in children with autistic disorder [60] and another reported significantly increased plasma serine in children with autism spectrum disorders [87] and significantly lower levels of serine were reported for platelet poor plasma in autism spectrum disorders [86]
The proximal tubules demonstrate vacuolar degeneration, interstitial edema, and protein deposition 87