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Human healing timelines are generally longer than animal models

Cognitive decline in humans typically starts in midlife and deepens with proceeding age, suggesting that age itself is the greatest risk factor

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Published evidence indicates that B12 deficiency can make HbA1c unreliable, but the direction of the distortion whether the result is spuriously high or spuriously low is variable and may depend on the degree of anaemia, the specific HbA1c assay used, and other concurrent conditions