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The REDEFINE 1 trial found that when evaluating the treatment effect regardless of whether patients stayed on treatment, those treated with CagriSema achieved weight loss of 20.4% (from an average baseline body weight of 236 lb) at 68 weeks versus 3.0% (from an average baseline body weight of 235 lb) for the placebo group which was statistically significant

As part of our approach, we provide education and guidance on lifestyle modifications, exercises, and self-care techniques to support ongoing progress and prevent recurrence of symptoms

The theoretical basis seems sound, though comparative data remains limited

Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury