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Deteriorated clearance mechanism leads to the accumulation and sensitization of -synuclein in vivo , thereby increasing the risk of developing PD (Lei et al., 2019)

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Dietary iron is absorbed primarily in the proximal small intestine, a process positively regulated by hypoxia-inducible factor-2 (HIF-2) ( 2.2 Core characteristics of ferroptosis Ferroptosis is an iron-dependent form of programmed cell death driven by lipid peroxidation

Thinning skin, a hallmark of aging that leaves blood vessels more visible and skin more susceptible to tearing, begins to reverse as GHK-Cu restores dermal architecture