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10.1016/j.jphs.2014.12.010 61 LiuT.YangL.GaoH.ZhuoY.TuZ.WangY.et al (2022)

T2DM and hyperglycemia are also associated with oxidative stress from the overproduction of reactive oxygen species (ROS) and decreased efficiency of scavengers systems ( Furthermore, our lab has previously shown that individuals with T2DM have lowered levels of GSH due to decreased levels of both GCL and GSS protein compared to healthy subjects ( M

The progressive nature of CKD may progress to end-stage renal disease (ESRD), which requires renal transplantation or treatment with dialysis [51,196,197]