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vitamin B12 AHUMAN NECESSITIES A61MEDICAL OR VETERINARY SCIENCE

Purity is attained using an advanced distillation process that involves fermentation, centrifugation, cell extraction, filtration, and crystallization

12.6 Pathways of biliverdin production from heme by chain-opening and bilirubin production by reduction of biliverdin (Reproduced with permission from Odell [15]) After its formation in reticuloendothelial cells, bilirubin is released into the bloodstream, where it is transported bound to albumin via one primary and two secondary binding sites