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Systemic MCAS Reactions: By "hiding" dietary proteins from hyperactive mast cells, targeted enzymes help reduce the likelihood of massive histamine dumps that cause systemic flushing, hives, itching, and sudden drops in blood pressure

What is missing from the gym version of the conversation is the part that protects the patient: licensing, clinical evaluation, regulated sourcing, and follow up

National Institutes of Health Accessed October 29, 2025

The genetic possibility of errors cannot be totally excluded, but the consensus is in favor of an environmental problem affecting epigenesis and methylation [2,47,48,49,54,55,56]