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As with doxorubicin, cisplatin treatment also results in ROS generation, which is neutralised by the NADPH-powered glutathione system, warranting investigation of this strategy for other forms of chemotherapy which are detoxified via this system

In patients with T2D, GLP-1RA were associated with a 21% reduction in composite kidney outcomes mostly driven by amelioration of albuminuria 80

Subsequent increased capillary membrane permeability and fluid buildup in lungs and explains the development of ARDS requiring the need for mechanical ventilation

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