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However, its important to note that while staying hydrated may influence how alcohol affects the body, it does not significantly change how quickly the liver metabolizes alcohol

Based on the studies with isolated perfused rat liver, Masuda [59] suggested that covalent binding of carbon tetrachloride metabolites rather than lipid peroxidation has a significant role in the production of centrilobular necrosis following carbon tetrachloride administration

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NAPQI-alkylated peptides found by database searching were confirmed by using the following criteria: 1) precursor mass error 95%, 3) the presence of one diagnostic production (see Figure 3) (Sleno et al., Table 3)