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Meanwhile, on day 28, the control-group grafts showed a well-defined lobulated mass of inhomogeneous signal intensity with a hypointense rim, corresponding to a low survival status

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Their functional enrichment analyses linked these genes to mRNA metabolic processes, immune cell regulation, and RNA transport pathways, confirming their potential role in OA pathogenesis and immune-mediated joint degradation (Huo et al., 2025)

Hypoxia-inducible factor-2 in rheumatoid arthritis: regulation and pathophysiological role