Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]
Studies have shown that quercetin can reduce airway hyperresponsiveness, eosinophilic inflammation, and mucus hypersecretion, which are the major characteristics of asthma [163]
INTRODUCTION As one of the driving forces behind the cellular detoxification machinery, glutathione S -transferases (GSTs) and especially the pi class glutathione S -transferase P1 (GSTP1) is currently in the focus of the cancer research community, evaluating the relevance of GSTP1 epimutations for cancer development and its potential as a major epigenetic cancer biomarker
NYHA: New York Heart Association