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they include the superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), singlet oxygen ( 1 O 2 ) and the hydroxyl radical (HO )

2.6 Mitochondrial morphology The ultrastructural changes associated with iron-induced ferroptosis, with special attention on mitochondrial morphology, were assessed using transmission electron microscopy (TEM)

This review summarizes CHE as a multi-organ syndrome, focusing on the gut-liver-muscle-brain axis, diagnosis, treatment, and future challenges and directions for clinical implementation

The randomization sequence was computer-generated by a statistician, and allocation concealment was maintained by an independent researcher