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Additionally, damaged mitochondria release mtDNA into the cytosol, activating the innate immune system via damage-associated molecular patterns (DAMPs) (251, 377), modulating both innate and adaptive immune responses (377379)

Therefore, AMSCs treatment can promote mitochondrial biogenesis and mitophagy, thereby increasing OXPHOS and restoring mitochondrial function

While it's essential to consider financial factors, the benefits of maintaining optimal B12 levels far outweigh the price tag

So, while the idea that B12 injections cause weight gain might be a popular rumor, current evidence indicates that a vitamin B12 deficiency is unlikely to affect your weight directly in terms of gain