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Gomisin J was shown to suppress proliferation and induce necroptosis in the breast cancer cell lines MCF7 and MDA-MB-231, particularly in apoptosis-resistant cancers, making it a potential therapeutic for hard-to-treat malignancies [83]

We explore new methods that enhance the protective role of mucus through physical reinforcement, pathogen neutralization, muco-trapping and rehydration, as well as strategies that overcome the mucus barrier to improve drug delivery, including physical modulation, mucoadhesive design, muco-penetrating design, mucolytics and active targeting

T.KhanH.KhalidA.MahmoodS

Malladi P, et al