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Generic name Cyanocobalamin 2 mL Manufacturer Pliva Pakistan (Pvt) Ltd

Standard esophageal HRM can be supplemented with adjunctive tests such as the multiple rapid swallow sequence, during which a patient is instructed to swallow water every 2 seconds for 5 swallows to assess inhibitory input and peristaltic reserve, and a rapid drink challenge to assess functional obstruction at the esophagogastric junction (EGJ)

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Their half-lives are comparable (a few minutes in the periphery, prolonged action in the central nervous system)