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One proposed mechanism involves modulation of neurotransmitter systems in the brain, particularly GABAergic, opioidergic, serotonergic, and dopaminergic pathways that are known to regulate sleep, arousal, mood, and stress responses

Exposure to EMF has been linked to heightened formation of reactive oxygen species (ROS) [12] as stated earlier, ROS generation can also occur aside from the previously mentioned EMF, including, radioactivity, stress, cigarette smoke, and redox processes within the body [5]

FIGURE 3 3.2 Signal of system organ class In the disproportionality analysis, 24 SOCs were implicated in AEs related to both anakinra and canakinumab

a , Immunoblot analysis of control (shCtrl) and GDH1 knockdown (shGDH1) cancer cell lines