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Additionally, the reduced plasma levels of brain-derived neurotrophic factor (BDNF) observed in BIPN patients may be associated with BTZ-mediated inhibition of platelet aggregation and activation, which in turn leads to decreased BDNF release and consequently impairs its neuroregenerative effects on peripheral nerves (Nishiwaki et al., 2020)

In contrast, several SRCR domains that have neither ions bound nor conserved ion binding residues (structures in the second row in Fig

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By enhancing red blood cell production and ensuring efficient oxygen delivery, B12 helps mitigate the fatigue that often accompanies weight loss efforts