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Because NAC simultaneously prompts mast cells to release histamine and prevents the body from breaking that histamine down, it can trigger severe symptom flaressuch as hives, sinus drainage, anxiety, and flushingin highly sensitive MCAS patients

Emergency medicine physicians often view IV therapy as appropriate for severe dehydration but unnecessary for mild hangovers in otherwise healthy individuals

Its not always the case, but it is very often the case

Studies suggest somewhere around 250500 mg taken orally each day can meaningfully affect both brightness and overall tone, with some mild anti-aging effects showing up in the process [1][2]