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Groups A-C were associated with significantly increased H3K27ac and H3K4me1 signals around the ATAC-seq peak and groups D-F were associated with significantly decreased signals ( Figure 1C and Supplementary Figure 2 )

GHK-Cu supports cellular repair, tissue regeneration, and skin health, making it ideal for those focused on optimizing systemic recovery and skin quality

The WT or mutant plasmids were then transfected into HNF4-negative SNU449 cells together with the control pRL-TK (Renilla Luciferase, Promega), and the control pcDNA3 vector or pcDNA3-HNF4 construct