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Similarly, zinc chloride (ZnCl2) and sodium selenite (Na2SeO3) promote oocyte progression to metaphase II during IVM, increasing TAC and reducing hydrogen peroxide (H 2 O 2 ) and MDA levels, which correlate with upregulated antiapoptotic and antioxidative gene expression ( 2.3 Epigenetically regulated metabolic pathways Epigenetically regulated metabolic pathways play a pivotal role in enhancing oocyte quality and developmental competence

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