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This mechanism may be due to the high enrichment of miR-200a in EVs derived from HESCs, which downregulates Keap1, a negative regulator of Nrf2 expression, thereby playing a crucial role in the angiogenic process mediated by these vesicles ( 3.4 The role of EVs in the development of asthenozoospermia Asthenozoospermia (AS) is one of the common causes of male infertility, characterized by a lower proportion of progressively motile sperm in semen parameters than the reference limit

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Instead, it frames the page as a research-documentation resource