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Bottom line: Topical use is low-risk and low-cost

It shields cells from many forms of damage, including oxidative stress, toxins, and ischemia (reduced blood flow)

What remains to be established is the full combination effect in long-term human trials

Using slightly less strict parameters, we also identified a potential association between raised IGF-1 and increased risk for melanoma (skin cancer) and myeloma (cancer of the bone marrow)