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While it is not a replacement for rest, proper nutrition , hydration, or a structured exercise plan, it may be considered as part of a broader wellness and recovery approach

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However, an RCT on 35 patients with migraine, showed that supplementation with N-acetylcysteine (1,200 mg), vitamin E (500 IU), and vitamin C (1,000 mg) daily for 3 months resulted in lower frequency, severity, and duration of headaches and lower acute medication use (90)

When they are stopped, production returns to its baseline rather than crashing