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Risk Factors for Oral Cancer While oral cancer can affect anyone, certain factors increase your risk: Tobacco use (cigarettes, cigars, pipes, chewing tobacco, snuff) the #1 risk factor Heavy alcohol consumption especially combined with tobacco use HPV infection (human papillomavirus, particularly HPV-16) increasingly the leading cause of oropharyngeal cancers in younger adults Prolonged sun exposure increases risk of lip cancer Age risk increases significantly after age 45 Gender men are roughly twice as likely as women to develop oral cancer Poor nutrition diets low in fruits and vegetables may increase risk Previous oral cancer diagnosis significantly increases risk of recurrence Even if none of these apply to you, regular screening is still recommended

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