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To assess the metabolic stability of the synthesized peptides, serum metabolism studies were conducted using blood obtained from 4-month-old male Sprague-Dawley rats

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A case series published in the American Journal of Health-System Pharmacy documented allodynia specifically associated with semaglutide, and a Cureus publication detailed dysesthesia and allodynia with both semaglutide and tirzepatide

Potential side effects and the importance of medical supervision While many patients tolerate these therapies well, potential side effects can include injectionsite reactions, digestive upset, or allergic responses