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Furthermore, the chronic inhalation of ECV (1-hour Daily for 1 to 4 months) has been reported to induce airway hyper-reactivity and air space enlargement in exposed mice [11, 12] as well as mucin production [13] some of these effects being nicotine-dependent [14]

(1940) Frank Proffitt first sang the murder ballad "Tom Dula" for Frank and Anne Warner in 1938 in Beech Mountain, North Carolina, and recorded a portion of it two years later, accompanying himself on a banjo of his own making

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