Meanwhile, it can also modulate the activities of many signaling molecules and redox-sensitive transcription factors through S -glutathionylation, a form of posttranslational modification that combines cysteine residues with GSH
"True radiance starts at the cellular level
Prodrugs of GST Both conventional chemotherapeutic and targeted agents have well-established toxicity profiles, with a wide range of adverse effects, eg, bone-marrow suppression, gastrointestinal toxicity, immunosuppression, gastrointestinal toxicity, hepatotoxicity, and cardiotoxicity
Besides GST, other members of the GSH-redox system, such as glutamate cysteine ligase, 31 glutathione peroxidase, and glutathione reductase, also play significant roles in this process