It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase)
this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization
displaying a strong preference for the (R
Specificity: Phospho-NR3C1 (Ser203) Antibody detects endogenous levels of NR3C1 only when phosphorylated at Serine 203
SRp46 (E72) Polyclonal Antibody-BS9165 Cells on 3D Scaffolds It binds the sterol-sensing domainsSRp46 (E72) Polyclonal Antibody Product: Rabbit IgG, 1mg ml in PBS with 0. 02% sodium azide, 50% glycerol, pH7. 2 Catalogue Numbers: BS9165 50, BS9165 100 Sizes: 50l, 100l Swiss Prot: Q9BRL6 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, IHC Background: The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine serine (RS) rich domain, are essential for constitutive splicing and also regulate splicing