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For lupus researchers, this raises interesting questions about protocol design

Such C-terminus optimization will be essential for S export and a robust immune response to genetic vaccines against the wide diversity of C-terminal residues in S proteins encoded by CoVs of human concern, including the lethal MERS-CoV and human CoV OC43 associated with common cold-like symptoms 43,71

This conversion can trigger proteotoxic stress and abnormalities in enzymes containing sulfhydryl groups, highlighting the significance of maintaining optimal glutathione levels for overall health and neurological function